Genetic Mutation Data Indicates Ovarian Cancer Risk
January 6, 2022Cedars Sinai scientists have found the origins of a common ovarian cancer by modeling fallopian tube tissue, allowing physicians to determine how genetic mutations increase an individual’s risk of cancer.
Through the created tissue, scientists can predict patients who may develop ovarian cancer, allowing for early detection and prevention strategies.
According to the American Cancer Society, ovarian cancer is the leading cause of gynecologic cancer deaths in the United States due to mild symptoms and difficult tumor detection. While the lifetime risk of developing ovarian cancer is less than two percent for the general population, the estimated risk for individuals who carry a mutation in the BRCA-1 gene is between 35 and 70 percent.
In the study, the research team generated induced pluripotent stem cells (IPSCs). The researchers started with blood samples taken from two groups of women: young ovarian cancer patients who had the BRCA-1 mutation and a control group of healthy women.
Source: https://healthitanalytics.com/news/genetic-mutationdataindicatesovarian-cancer-risk